Structural requirements for cub domain containing protein 1 (CDCP1) and Src dependent cell transformation.
Cub domain containing protein 1 (CDCP1) is strongly expressed in tumors derived from lung, colon, ovary, or kidney.It is a membrane protein that is phosphorylated and then bound by Src family kinases.Although expression and phosphorylation of CDCP1 have been investigated in many tumor cell lines, the CDCP1 features responsible click here for transf